Yes — Strasbourg is generally a very safe city for tourists, consistently ranking among France's more secure destinations outside the major risk zones. Violent crime targeting visitors is rare, and the main tourist areas around Petite France, place de la Cathédrale, and the Grande Île are well-patrolled and lively until late.
Practical tips:
Pickpocketing and bag-snatching are the most realistic risks, particularly during the Christmas market (when dense crowds and distraction are at their peak) and around Gare de Strasbourg at night. Keep bags zipped and in front of you in crowded areas.
The immediate surroundings of the train station (Gare Centrale) can feel rough after dark — exercise the same awareness you would in any large European city. A few streets to the north and east, the atmosphere rapidly improves.
The city centre is compact and extremely walkable; there is rarely any reason to be in an unfamiliar area late at night.
Strasbourg has an effective tram and cycle network, minimising the need for late-night taxis. Use the official Vélhop/Véloparc bike share or book rides through licensed apps.
For solo women travellers, Strasbourg is considered among the safer French cities. The well-lit, busy old town is comfortable to navigate alone at night.
As in any major European city, stay aware of your surroundings, don't leave bags on café chairs unattended, and keep a copy of your passport separate from the original.